N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M

N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M - Names and Identifiers

Name	N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M
Synonyms	BOC-LEU-NME(OME) BOC-LEU-N(OME)ME BOC-L-LEUCINE N,O-DIMETHYLHYDROXAMIDE Boc-L-Leucine N,O-Dimethylhydroxamide N-Boc-L-leucine N'-Methoxy-N'-MethylaMide N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M N-(tert-Butoxycarbonyl)-L-leucine N-methoxy-N-methylamide N~2~-(tert-butoxycarbonyl)-N-methoxy-N-methyl-L-leucinamide N-(TERT-BUTOXYCARBONYL)-L-LEUCINE N'-METHOXY-N'-METHYLAMIDE (S)-N-Methyl-N-methoxy-2-(tert-butoxycarbonylamino)-4-methylpentanamide (S)-tert-butyl 1-(methoxy(methyl)amino)-4-methyl-1-oxopentan-2-ylcarbamate (S)-tert-Butyl (1-((MethoxyMethyl)aMino)-4-Methyl-1-oxopentan-2-yl)carbaMate
CAS	87694-50-6
InChI	InChI=1/C13H26N2O4/c1-9(2)8-10(11(16)15(6)18-7)14-12(17)19-13(3,4)5/h9-10H,8H2,1-7H3,(H,14,17)/t10-/m0/s1

N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M - Physico-chemical Properties

Molecular Formula	C13H26N2O4
Molar Mass	274.36
Density	1.46g/mLat 25°C(lit.)
Boling Point	235°C(lit.)
Flash Point	>230°F
Storage Condition	2-8°C
Refractive Index	n20/D 1.454(lit.)
Use	This product is for scientific research only and shall not be used for other purposes.

N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M - Risk and Safety

WGK Germany

N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M - Introduction

N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N '-M, also known as N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N'-M, is an organic compound.

Nature:
1. appearance: common solid, generally white crystal or crystalline powder.
2. Melting point: According to laboratory records, its melting point is between about 132-136°C.
3. molecular formula: C16H30N2O5
4. Molecular weight: 338.42g/mol
5. solubility: soluble in some organic solvents such as methanol, ethanol and dichloromethane, slightly soluble in water.

Use:
The compound is commonly used in the synthesis of amine protecting groups in organic synthesis and targeted drugs.

Preparation Method:
The method for preparing this compound can be divided into multiple reactions. The specific steps are as follows:
1. Taking tert-butyl methyl 2-carbamate and dimethyl methyl malonate, (S)-tert-butyl methyl 2-aminomethylmalonate was prepared by transesterification.
2. The compound obtained in step 1 is reacted with methanol to obtain methyl (S)-tert-butyl 2-methoxymethylmalonate.
3. The compound obtained in step 2 is reacted with 1-chloromethyl-3-methylmalonate octyl ester to produce N-(tert-butoxycarbonyl)-L-leucine N'-methoxy-N '-M.

Safety Information:
The compound is generally stable and relatively safe under normal operating conditions. But still need to pay attention to the following matters:
1. avoid contact with skin and eyes, avoid inhalation or ingestion.
2. During operation, be sure to wear appropriate personal protective equipment, such as gloves, goggles and laboratory coats.
3. It should be operated in a well-ventilated laboratory environment to avoid the accumulation of harmful gases.
4. In case of contact with the compound, rinse immediately with plenty of water and seek medical attention immediately.

Please note that the above information is for reference only and specific properties, uses, manufacturing methods and safety information should rely on laboratory manuals, safety data sheets and professional guidance.

Last Update：2024-04-09 15:18:00